Date of Award
The intestinal microflora are capable of performing a wide variety of metabolic transformations. "The intestinal bacteria can enhance the function of the entire gastrointestinal tract, protect against pathogenic, maintain the vital chemical balance of the gastrointestinal system, and produce needed vitamins and hormones" (http;//www.upwardquest.com/crit2.html). Some of the products of this metabolism have been associated with carcinogenic processes, such as cancer, tumor formation, gastrointestinal disease, and infections. The ability of human intestinal microbes to interact with metabolites directly or after recirculation may contribute toward different toxicological disorders and disease.
The purpose of this study is to characterize and isolate the azoreductase gene in Citrobacter freundii.
Todd, Syndia S., "Molecular Screening Of Azoreductase Gene and Its Activity in Human Intestinal Bacteria" (2006). McCabe Thesis Collection. Paper 37.